REVIEW ARTICLE
Year : 2013  |  Volume : 12  |  Issue : 2  |  Page : 95-108

Structure and physicochemical properties in relation to drug action


Department of Therapeutical Chemistry, National Research Centre, Giza, Egypt

Correspondence Address:
Yasmin M Syam
Department of Therapeutical Chemistry, National Research Centre, Dokki 12311, Giza
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1687-4315.124000

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In this review, classification of drugs, chemical structure, and biological activity, examples of pharmacological activities of some structural moieties, bioisosterism, physicochemical properties in relation to drug action, drug-receptor theory, acid-base chemistry in formulation and biodistribution of the drug, quantitative structure-activity relationship, and molecular docking are briefly presented with examples.


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