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  Indian J Med Microbiol
 

Figure 4: A photomicrograph in the liver of (a) the control group showing normal central vein and hepatocyte architecture; (b) rats treated orally with a high dose of nano-hydroxyapatite (Hap) (300 mg/kg body weight) showed a normal histological structure of the central vein and surrounding hepatocytes; (c, d) rats treated orally with a low dose of nano-HAp (150 mg/kg body weight) showed a normal structure of hepatocytes, portal vein, and bile ducts; (e) rats treated subcutaneously with nano-HAp (600 mg/kg body weight) showed a normal structure of hepatocytes. H&E, ×100.

Figure 4: A photomicrograph in the liver of (a) the control group showing normal central vein and hepatocyte architecture; (b) rats treated orally with a high dose of nano-hydroxyapatite (Hap) (300 mg/kg body weight) showed a normal histological structure of the central vein and surrounding hepatocytes; (c, d) rats treated orally with a low dose of nano-HAp (150 mg/kg body weight) showed a normal structure of hepatocytes, portal vein, and bile ducts; (e) rats treated subcutaneously with nano-HAp (600 mg/kg body weight) showed a normal structure of hepatocytes. H&E, ×100.